Tuesday, July 14, 2009

Esophageal cancer

Even if statistically esophageal cancer is the 8-th most frequently occurring type of cancer, it still produces much higher rate of lethal oucomes because it is nearly impossible to detect it at early stages, while at late stages there is practically no way to have it cured.

To put it in plain words, esophageal cancer developes from a malignant tumor in the esophagus (muscular tube connecting pharynx (throat) and stomach, through which food passes when you eat it).

Esophageal cancer sympthoms like difficulty or pain in course of swallowing are normally noticed and paid attention to at the stages when it is too late, while an unusually husky or raspy voice that may be an esophageal cancer sympthom at relatively early stage hardly puts a person on alert and prompts him or her to consult a specialist like it should. Generally, due to lack of early sympthoms, as a rule patients are diagnosed with esophageal cancer only when they need to undergo endoscopy for a bleeding ulcer, anaemia, heartburn etc.

To be realistic, efforts should be focussed on what can be done to prevent the development of this mortal condition by a person himself or herself. On the whole, to reduce the risks of esophageal cancer, an individual should care to assure he/she receives adequate and healthy nutrition, while adequate dental care is simply vital.

What can be done specifically to reduce esophageal cancer risk

The heavier you smoke, the greater is your risk of falling ill. The same pertains to drinking very hot tea, low quality spirits, or excessive alcohol drinking. The study by the Dutch throat cancer researchers revealed connection of 2 two forms of esophageal cancer with smoking. They also discovered evident and strong connection between drinking and at least one other form of esophageal cancer. According to Jessie Steevens of the Department of Epidemiology at Maastricht University, an average person taking 4 glasses of alcohol a day expose themselves to 5 times bigger risk of developing the cancer compared to a none-drinker. From the other hand, several other sources say moderate consumption of good quality read wine reduces the risks of developing esophageal cancer by more than 50%, supposedly due to antioxidants contained in wines.

You are decreasing the risk of developing esophageal cancer, if you are:
  • Using aspirin or related drugs
  • Consuming cabbage, broccoli, cauliflower, green and yellow vegetables, and fruits
  • Moderate coffee drinker
Your have increase risks of developing esophageal cancer, if you are:
  • Over 60 years of age
  • If you are male
  • Have close relatives with cancer
  • Tobacco smoke or heavy alcohol driker, or both
  • Suffering from Gastroesophageal reflux disease (GERD)
  • Infected with human papillomavirus (HPV)
  • Using dietary substances like nitrosamine
  • Having medical history of other head and neck cancers
  • Plummer-Vinson syndrome (anemia and esophageal webbing)
  • Tylosis and Howel-Evans syndrome
  • Someone who underwent radiation therapy
  • Obese
  • Hot beverages, especially hot brewed tea drinker
What's new

MD Anderson Cancer Center in Houston, Texas, analyzed 210 esophageal cancer cases and revealed potentially critical importance of the so-called genetic variations within the PI3K/PTEN/AKT/mTOR pathway that could be used to possibly define inherent resistance to certain chemotherapeutic agents and radiation in some patients. This sort of genetic testing might turn out a novel way to hopefully begin controlling the esophageal cancer evolution to at least slow down the desease progressing.

Other queries: diagnostics and therapy * survival rate esophageal cancer * dragon database * gene transcription * EC-implicated genes * DDEC * EC genetics * Barrett's esophagus

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